Mass Spectrometry of Biological Fluids

Bios-Therapy, Physiological Systems for Health SpA operates in the research and development of new molecular complexes obtained from natural substances by means of biotechnological processes, for the health of man, animals and plants, studying and selecting natural raw materials and all production processes from seed to finished product; specific systems composed of RNA and DNA are particularly researched and validated for their rebalancing activity in living organisms. The fields of application of the substances obtained, both single and mixed, are mainly aimed at degenerative, metabolic and oncological diseases.

We offer a placement opportunity in Bios-Therapy, Physiological Systems for Health SpA for a Scientist.

KEY RESPONSIBILITIES

• Perform complex untargeted and targeted experiments to study and analyse the effect of natural substances on specific cellular and molecular processes. The mass spectrometry analyst will be responsible for sample preparation and processing, including extraction, purification and other pre-analytical treatments starting from celi lysates or human blood, following established or to be established protocols in order to perform routine, extra routine and complex analytical assays using mass spectrometry techniques {LC-qToF, LC-QQQ) to identify, quantify and analyse compounds in various matrices. Knowledge of spectroscopic techniques such as NIR, FTIR and RAMAN is a plus.
This position involves working within a laboratory setting to support research, quality control, and regulatory compliance. The goal is to deepen the understanding of underlying biological mechanisms and cellular responses, creating a solid foundation for the development of new therapeutic applications
• Troubleshoot and resolve technical issues with MS instrumentation and software, coordinating with service providers as needed
• The successful candidate is expected to interact on a daily basis with wet-lab scientists in order to generate persona! relationships and the relevant technical environment necessary to enable a comprehensive Systems Biology approach.
• The successful candidate is expected to work independently, in the framework of collaborations with international academic institutions.

REQUIREMENTS

•    Ph.D. in biochemistry or molecular biology with experience working with mass spectrometry or minimum of 2 years of experience working with mass spectrometry techniques (LC-qToF, LC-QQQ, GC-MS) in a laboratory setting.

•    Scientific background (CTF, Bio-technology, Chemistry or a relateci field)
•    Strong technical knowledge of mass spectrometry principles, instrumentation, and data interpretation. Experience in sample preparation and processing, including extraction, purification, and other pre-analytical treatments.
•    Experience with method development and validation in mass spectrometry.
•    Excellent problem-solving skills and attention to detail in data collection and analysis.
•    Knowledge of the process of targeted and non-targeted analysis.
•    Knowledge of Data Analysis.
•    Experience with Agilent instrumentation will be considered a valuable asset.
•    Knowledge of biochemistry and pharmacology will be considered a valuable asset.
•    Knowledge of spectroscopic techniques such as NIR, FTIR and RAMAN will be considered a valuable asset.
•    Fluent in English.

Bios-Therapy, Physiological Systems for Health SpA is committed to diversity and inclusion and offers a respectful work environment, free from discrimination and harassment. Candidates are selected without distinction of race, colour, religion, sex, ethnic origin and regardless of disability, pregnancy status, sexual orientation, gender identity or expression, public assistance status, salary disclosure or related discussion, or any other protected classification.